Acyclovir

Genital Herpes
Initial treatment: 200 mg PO q4hr while awake (5 times daily) for 10 days or 400 mg PO q8hr for 7-10 days

Intermittent treatment for recurrence: 200 mg PO q4hr while awake (5 times daily) for 5 days; initiate at earliest sign or symptom of recurrence

Chronic suppression for recurrence: 400 mg PO q12hr for up to 12 months; alternatively, 200 mg 3-5 times daily

Herpes Simplex Virus Encephalitis
10-15 mg/kg IV q8hr for 10 days; up to 14-21 days reported

Herpes Zoster (Shingles)
Acute treatment: 800 mg PO q4hr while awake (5 times daily) for 7-10 days

For treatment of shingles: 800 milligrams (mg) five times daily for 7 to 10 days
For genital herpes treatment: 200 mg five times daily for 10 days
For preventing a recurrence of genital herpes: 400 mg every 12 hours for 12 months
For treating chicken pox in adults and children who weigh more than 40 pounds: 800 mg four times daily for 5 days

An overdose of acyclovir can cause kidney damage.

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